Puma Biotechnology cancer drug shows positive mid-stage results

Puma Biotechnology cancer drug shows positive mid-stage results

(Reuters) - Puma Biotechnology Inc said its experimental lung cancer drug was safe to be administered with an already approved treatment for the disease in a mid-stage study. The time where a patient's disease did not progress increased to four months when given a combination of Puma's PB272 and temsirolimus, compared to about three months when given only PB272, according to data from the study. All the patients in the study were given a high dose of the drug loperamide to prevent diarrhea related to PB272. There were no severe diarrhea events seen in the trial, the company said. ...

Seattle Genetics, Takeda's cancer drug meets main goal in trial

(Reuters) - Seattle Genetics Inc and Takeda Pharmaceutical Co Ltd said their approved cancer drug was successfully used as a consolidation therapy in a late-stage trial for patients with a type of lymphatic cancer. Consolidation therapy is given to cancer patients who have undergone initial therapy and kills any cancer cells that may be left in the body. ...

CORRECTION: Smartphone attachment eliminates doctor visits to diagnose ear infections

If you can't imagine an otoscope smartphone attachment, it's probably because the only time you've ever seen one was at the doctor's office. It's here: an otoscope that enables you to view and capture images of the ear canal and eardrum on the smartphone's screen, and a corresponding app that lets you snap a picture and send it to your doctor for diagnosis.

UN mission to combat Ebola opens HQ in Ghana

DAKAR, Senegal (AP) — The U.N. mission to combat Ebola is opening its headquarters in Ghana, where it will coordinate aid for the West African crisis.

Seattle Genetics, Takeda's cancer drug meets main goal in trial

(Reuters) - Seattle Genetics Inc and Takeda Pharmaceutical Co Ltd said their approved cancer drug was successfully used as a consolidation therapy in a late-stage trial for patients with a type of lymphatic cancer. Consolidation therapy is given to cancer patients who have undergone initial therapy and kills any cancer cells that may be left in the body. ...

India's Jaitley in isolation ward, may skip U.S. trip

By Manoj Kumar NEW DELHI (Reuters) - India's Finance Minister Arun Jaitley may have to cancel a trip to the United States in October after he was moved to an isolation ward of a government-run hospital to help him recover from an infection that followed a stomach operation to treat diabetes. Jaitley is due to attend a World Bank meeting on Oct. 10-12 in Washington, where he is also expected to meet senior government officials. He was due to leave on Oct. 8. "It seem doubtful that he would be able to take stress for the long journey to the U.S. ...

Full plates fight prejudice in Hungary restaurant

By Gergely Szakacs SZEKSZARD Hungary (Reuters) - Waitress Maria Kecskemeti says working with people is a daily challenge, requiring much skill and empathy. She also admits to initially being somewhat scared of how guests would react when she took the first orders from her wheelchair. Kecskemeti works at Izlelo, a restaurant set up in 2007 by a local foundation to help handicapped people find employment. She is one of 15 employees, most of whom have some type of disability like deafness or a learning disability. ...

Puma Biotechnology cancer drug shows positive mid-stage results

(Reuters) - Puma Biotechnology Inc said its experimental lung cancer drug was safe to be administered with an already approved treatment for the disease in a mid-stage study. The time where a patient's disease did not progress increased to four months when given a combination of Puma's PB272 and temsirolimus, compared to about three months when given only PB272, according to data from the study. All the patients in the study were given a high dose of the drug loperamide to prevent diarrhea related to PB272. There were no severe diarrhea events seen in the trial, the company said. ...

Tonix Pharma's pain drug fails mid-stage study

(Reuters) - Tonix Pharmaceuticals Holding Corp said its lead pain drug failed the main goal of a mid-stage study, sending its shares down by nearly half in premarket trading. The drug, TNX-102, is being tested to treat fibromyalgia, a chronic syndrome characterized by widespread pain and lack of sleep. The treatment failed the main goal of reducing pain experienced by patients by the 12th week of the trial, Tonix said. However, TNX-102 was shown to improve sleep quality in patients, while some subjects experienced a 30 percent reduction in pain, the company added. ...

Hundreds of firms join global hunt for copycat biotech drugs

By Ben Hirschler (Reuters) - Hundreds of companies around the world are chasing an emerging market for cheaper copies of costly biotech drugs, with more than 700 so-called biosimilars now in development or already approved, according to a major study of the sector. Biotech medicines - made from proteins and other large molecules - account for six of the 10 biggest-selling drugs in the world today, led by AbbVie's $12 billion-a-year rheumatoid arthritis injection Humira. ...

Merck immunotherapy drug shows promise in bladder cancer

MADRID (Reuters) - Merck & Co's new immune system drug Keytruda has produced encouraging results in early tests against bladder cancer, according to a company-sponsored study, prompting the firm to prepare a clinical trial later this year. Keytruda is the first in a new wave of immune-boosting medicines to be approved for treating melanomas in the United States, but it also has potential in a range of other cancers. ...

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